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NFL Week 17: Must-Know Matchups, Fantasy Insights, and Playoff Stakes

December 26, 2025
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NFL Week 17: Must-Know Matchups, Fantasy Insights, and Playoff Stakes

Week 17 NFL Schedule Overview

The Week 17 NFL schedule is packed with high-stakes matchups, critical for playoff positions following an exciting Christmas Day lineup.

This week, we get to experience some clashes that can fundamentally change the landscape of the playoffs.

Key Matchups to Watch

As teams scramble for playoff spots or the best positions for upcoming drafts, here are the games that could turn the tide for franchises:

Texans (10-5) @ Chargers (11-4)

Saturday, 4:30 p.m. ET | NFL Network

These teams clash again after a thrilling wild-card encounter last year. The Texans' defense, even more formidable this season, will face a surging Justin Herbert, who is fresh off a phenomenal performance. Houston's defense ranks first in the league with 272.3 yards allowed per game. Coach DeMeco Ryans has praised Herbert as one of the toughest quarterbacks. Can he stand against Texas' relentless pass rush? — Insights from DJ Bien-Aime

Ravens (7-8) @ Packers (9-5-1)

Saturday, 8 p.m. ET | Peacock

With playoff hopes on the line, the Ravens need a win to keep their postseason aspirations alive. Derrick Henry could shine in this matchup as he hunts for rushing yards to catapult him into the top 10 of the all-time list. Meanwhile, the Packers' defense has the potential to stifle the run. But how effective can Henry be against such a formidable defense? — Insights from Jamison Hensley

Seahawks (12-3) @ Panthers (8-7)

Sunday, 1 p.m. ET | CBS

The Seahawks are on a high following their nail-biting victory against the Rams. They are in a favorable position to claim the NFC West title if they can secure a win here. Meanwhile, the Panthers are pushing for a playoff berth themselves. Both teams will be giving it their all.

Weekly Predictions and Analysis

As always, let's break down predictions from our ESPN experts:

Chargers vs. Texans

Expert Picks:

  • Maldonado: Chargers 30, Texans 27
  • Moody: Texans 21, Chargers 17
  • Walder: Texans 23, Chargers 20

The projected winner leans in favor of the Chargers since they can clinch their playoff position with a win, but with the Texans fighting for their playoff lives, expect a heated clash.

Ravens vs. Packers

Expert Picks:

  • Maldonado: Packers 24, Ravens 22
  • Moody: Packers 24, Ravens 21
  • Walder: Packers 23, Ravens 17

The Ravens need a win, but the Packers have shown persistence. If the Ravens' defense stands tall, they could narrow the margin.

Fantasy Football Insights

As the regular season winds down, it's crucial to optimize your fantasy lineup:

Key Fantasy Players to Watch

  • RB Omarion Hampton (Chargers) has been a key asset, especially against a porous Texans defense.
  • WR Derrick Henry (Ravens) needs to shine to keep the Ravens playoff hopes alive.
  • RB Saquon Barkley (Eagles) is set for a major role following a consistent run of high scores.

Injury Report

Keep a close eye on injuries that could sway a game's outcome. As teams finalize their rosters, late injury news could change the landscape. For real-time updates, you can view the Texans injury report or the Chargers injury report.

Conclusion: A Thrilling NFL Week Ahead

Week 17 of the NFL season is packed with exciting opportunities and crucial matchups. Whether your focus is on playoffs or fantasy football, this week promises to deliver great action! Remember to keep your eyes on the key players, the injuries, and of course, the stakes.

Source reference: https://www.espn.com/nfl/story/_/page/viewersguide47389291/nfl-week-17-picks-predictions-schedule-fantasy-football-odds-injuries-stats-2025

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