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USC vs. Notre Dame: Key Betting Insights for Week 8 Showdown

October 17, 2025
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USC vs. Notre Dame: Key Betting Insights for Week 8 Showdown

Welcome to Week 8 of College Football!

With the electrifying clash between USC and Notre Dame on the horizon, sports betting enthusiasts have much to overcome in the lead-up to this epic showdown. This edition of the Newsweek Sports Betting newsletter dives into the heart of the action, providing insights that not only highlight critical betting odds but also decode the intricacies of matchups.

The Stakes Are High

This matchup is more than just a game; it's a battle with playoff implications. For Notre Dame, a loss would be catastrophic as it has already suffered two early-season defeats against ranked teams. USC, meanwhile, is looking to maintain momentum after a solid previous performance.

"The losers in other top matchups still have time to recover. But for Notre Dame, a loss could mean the end of their playoff hopes."

Current Odds and Betting Lines

Setting the stage: USC enters this showdown as an underdog. Here's a quick look at the latest betting information:

  • USC +9.5 (best odds: -108 at DraftKings)
  • Over/Under: 60.5 (best odds: -115 at DraftKings)

Some believe these spreads reflect the underestimation of USC's potential. After performing excellently in their last match, the Trojans have a lot to prove on Saturday night.

Key Matchups to Watch

Everything will largely depend on the quarterbacks. For USC, Jayden Maiava has shown impressive numbers this season with a completion rate of 71.9% and over 1,800 passing yards, while Notre Dame's performance against top-tier quarterbacks has raised questions.

  • **USC's Offensive Line**: Solid protection can dictate the game's pace.
  • **Notre Dame's Secondary**: After struggling against high-scoring offenses earlier this season, can they rise to the occasion?

My Best Bets

Given the circumstances, my top picks are:

  • **USC covering at +9.5** – Their recent form is hard to ignore.
  • **Over 60.5 points** – Both teams have explosive offenses ready to engage.

Final Thoughts

No matter how you slice it, this matchup promises high drama with significant ramifications in the playoff race. Whether you're a casual fan or an avid bettor, the excitement of USC vs. Notre Dame brings a thrill that simply cannot be matched. So gear up for a wild Saturday!

For more insights and betting recommendations, make sure to subscribe to our Sports Betting newsletter today!

Source reference: https://www.newsweek.com/sports/betting/newsletter-how-to-bet-college-football-week-8-usc-vs-notre-dame-odds-best-bets-10897124

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