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Week 5 Fantasy Football: Your Essential Start-Sit Guide

October 5, 2025
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Week 5 Fantasy Football: Your Essential Start-Sit Guide

Week 5 Fantasy Football: Start-Sit Rankings and Injury Reports

It's that time again—Week 5 is here, and fantasy managers are busy scrambling to make crucial roster decisions. With early Sunday games including the Vikings facing the Browns in London, every lineup choice counts more than ever. Here's what you need to know.

Lineup Decisions: Start 'Em or Sit 'Em?

This week, let's break down top players you should consider starting, and those you might want to avoid:

Must-Start Players

  • QB: Josh Allen (BUF), Jalen Hurts (PHI)
  • RB: Derrick Henry (BAL), Saquon Barkley (PHI)
  • WR: Amon-Ra St. Brown (DET), Justin Jefferson (MIN)
  • TE: Sam LaPorta (DET), Travis Kelce (KC)

Players to Sit

  • QB: Baker Mayfield (TB), Kyler Murray (ARI)
  • RB: J.K. Dobbins (DEN), Chase Brown (CIN)
  • WR: DeVonta Smith (PHI), Jerry Jeudy (CLE)
Remember, the matchups and current performance metrics often determine who can turn a fantasy team around.

Injury Updates: Who's In, Who's Out?

Before the first kickoff, you'll want to keep an eye on the injury reports. Some crucial updates include:

Inactives for Week 5

  • Lamar Jackson (QB, BAL) - OUT
  • CeeDee Lamb (WR, DAL) - OUT
  • Mike Evans (WR, TB) - OUT
  • Terrance Marshall (WR, CAR) - OUT

Confirmed Active

  • Jayden Daniels (QB, WAS)
  • Deebo Samuel (WR, WAS)
  • Michael Pittman (WR, IND)

Weather Insights for Your Lineups

Weather conditions can have a significant impact on gameplay and player performance. Monitor updates for potential rain or wind during games, especially for outdoor stadiums.

Final Lineup Tips

To maximize your chances of victory this week, keep your roster flexible. Monitor injury reports, react quickly to breaking news, and make sure to stay informed on players' matchups leading into game day.

It's crucial to be proactive, as surprises can strike at any moment during the season. As the games unfold, check in on player performances and adjustments that may need to be made.

For More Insights

For ongoing updates, check out our live tracker for fantasy news and pregame reports. Make sure you're equipped with all the information necessary for a successful fantasy line:

Stay engaged and keep your competitive edge alive in your fantasy league!

Source reference: https://www.sportingnews.com/us/fantasy/news/fantasy-football-week-5-sunday-rankings-start-sit-tracker-2025/60115cdbd1cfd384d3db95d2

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